17α-hydroxyprogesterone CAS 68-96-2

Introduction 17 α- Hydroxyprogesterone, sometimes referred to as Hydroxyprogesterone (English: hydroxyprogesterone, OHP), is an endogenous progesterone steroid similar to progesterone, and is also the precursor of biosynthesis of many endogenous steroid hormones, including androgen, estrogen, glucocorticoid, mineralocorticoid and kèk neurosteroids. Bioaktif 17-hydroxyprogesterone (17-OHP) se yon pwojestewòn andojèn ak yon entèmedyè chimik nan byosentèz la nan lòt òmòn esteroyid. Nan etid in vitro 17 α-OHP se yon pwojestewòn tankou agonist reseptè chemobookin, byenke efè li se relativman fèb. Li se tou yon entèmedyè chimik nan byosentèz la nan òmòn esteroyid tankou androjèn, estwojèn, òmòn sèks, glikokortikoid, ak mineralocorticoids. Nan etid vivo 17 Hydroxyprogesterone se yon endis esteroyid efikas pou GVBD (repwodiktif vezikul rupture). Pwopriyete chimik kristalize (asetòn/hexane). Pwen k ap fonn 221 ℃ (219-220 ℃). [α] 20/d+97 ° (chlorofor